Solution for continuous
core temperature monitoring

Solution for continuous core temperature monitoring

The temperature variable is a key indicator of the patient’s febrile state. The continuous nature of the measurement is quite difficult to obtain and only a few restrictive devices (rectal, esophageal probes, etc.) allow continuous core temperature monitoring.

e-Celsius Medical, class IIB medical device, is a miniaturized electronic ingestible capsule that transmits core temperature data continuously.

This capsule communicates in real time with a dedicated monitor, e-Viewer Medical, at a sampling period of 30 seconds. This monitor allows data recording and an alert may be triggered if a threshold has been exceeded. The communication distance between the capsule and the monitor ranges from 1 to 3m (depending on environment and patient).

The capsule also has its own memory. In the case of a communication disruption between the monitor and the capsule, an a posteriori automatic synchronization of the data is performed.

The capsule is removed on the natural way; the operational lifetime corresponds thus to the transit time (24-48h on average). The capsule is a single-use device delivered sterile and in a stand-by mode. An activation box allows you to associate the e-Celsius Medical capsule with the e-Viewer Medical monitor. A single monitor can manage up to three capsules simultaneously for mid/long term uses.

A dedicated interface, PC and MAC compatible, retrieves data for archiving or clinical use.

Key figures

e-Celsius Medical capsule

  • Delivered sterilized
  • Storage: 2 years
  • Weight: 1.7g
  • Size: 17.7mm x 8.9mm
  • Sampling period: 30sec
  • Accuracy: 0.2°C
  • Calibration range: 25°C to 45°C


  • FIFO memory: 2000 data capacity
  • Data transfer: RF transmission (433 – 434MHz)
  • Communication range: 1-3m
    (environment and patient dependant)
  • Life duration: 20 days

e-Viewer Medical monitor

  • 3 capsules per monitor
  • Multichannel: 7 monitors in parallel
  • Storage: 150 185 data per capsule
  • Autonomy: 24/36h
  • Size: 120mm x 70mm x 15mm
  • Activator size: 69mm x 59mm x 31mm

Main benefits

Designed by physiologists, the solution was developed to combine comfort and ease of use. It allows continuous core temperature monitoring and meets the key constraints for patient care:

Preservation of comfort and mobility;

Improve medical decision-making through reliable and accurate data and access to a complete data history;

Limit artifacts associated to the operator.

eCelsius performance - body temperature measurment

e-Celsius Medical capsule

eCelsius monitor - body temeperature measurment

e-Viewer Medical monitor

Various applications: research & clinical

The e-Celsius Medical solution allows continuous core temperature monitoring to diagnose or control the patient’s febrile state. Three main applications will be firstly covered: infectious diseases, oncology and sleep disorders.


Temperature monitoring in infectiology is critically important; fever is indeed a fundamental clinical sign facilitating the implementation of an early and appropriate therapy.

Continuous core temperature monitoring, without human intervention, make possible to reduce medical response times and improve diagnosis reliability, patient comfort and patient care.


Early detection of peak fever is critical for patients treated with chemotherapy and presenting a high risk of febrile illness (aplasia, febrile neutropenia, …). The possibility to continuously monitor the evolution of the temperature variable allows to ealry detect fever pic and thereby reduce the response time for medical staff.

The rapid initiation of antibiotic treatment in a context of severe immunosuppression limits the risk of serious infection (septic shock) which can lead to the death of the patient. This can probably shorten the length of the hospital stay. As soon as the temperature exceeds 38°C, we consider that it is the trigger to start a treatment.

Pr Jardin,
Unicancer - Rouen, France


The core temperature is a key indicator of the biological rhythmicity of the subjects. Continuous monitoring of this variable allows to characterize the circadian rhythm of the core temperature, which is an essential tool for sleep analysis and the diagnosis of sleep disorders.

Scientific references:

Huang et al., 2019, Ingestible sensors correlate closely with peripheral temperature measure in febrile patients.

Zucarelli et al, 2020, Obese Patients Decrease work rate in order to keep a constant target heart rate

Qu et al., 2020, Targeted temperature management at 33 degrees Celsius in patients with high-grade aneurysmal subarachnoid hemorrhage a protocol for a multicenter randomized controlled study

Webster et al., 2020, Using Circadian Rhythm Patterns of Continuous Core Body Temperature to Improve Fertility and Pregnancy Planning

Huang et al., 2021, Telemonitored Human Circadian Temperature Dynamics During Daily Routine

Moussalem et al.,2021, Effect of Phase Change Material Cooling Vests on Body Thermoregulation and Thermal Comfort of Patients With Paraplegia A Human Subject Experimental Study

Please contact us if you need more references.

The solution is not yet released – CE medical certification process is ongoing.

If you are interested in the e-Celsius Medical solution, Contact us

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